Tumour Necrosis Factor and Related Cytotoxins is popular PDF and ePub book, written by Gregory R. Bock in 2008-04-30, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Tumour Necrosis Factor and Related Cytotoxins can be Read Online from any device for your convenience.
Tumour Necrosis Factor and Related Cytotoxins Book PDF Summary
The number of factors implicated in the regulation of cell proliferation and differentiation is already considerable and more are continually being identified. This book concentrates on tumor necrosis factor (cachectin) and lymphotoxin, but includes observations of their interactions with other cytokines, especially the interferons and interleukins. TNF can be either cytostatic or cytotoxic to cultured cell lines, and a variety of mechanisms are proposed, ranging from DNA fragmentation to activation of phospholiopases. TNF is also reported to stimulate the growth of normal fibroblasts in vivo. The in vivo actions of TNF described here include haemorrhagic necrosis of tumors, cachexia, effects on the vasculature, and antiparasitic and antiviral activities. Also presented is some interesting data from the first stages of clinical trials of TNF as an anticancer agent.
Detail Book of Tumour Necrosis Factor and Related Cytotoxins PDF
- Author : Gregory R. Bock
- Release : 30 April 2008
- Publisher : John Wiley & Sons
- ISBN : 9780470513538
- Genre : Medical
- Total Page : 252 pages
- Language : English
- PDF File Size : 11,9 Mb
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