Toll like Receptors in Inflammation is popular PDF and ePub book, written by Luke A.J. O'Neill in 2006-03-16, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Toll like Receptors in Inflammation can be Read Online from any device for your convenience.
Toll like Receptors in Inflammation Book PDF Summary
A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of microbial products. Notable examples include TLR4 which recognizes LPS from gram negative bacteria, TLR3 which recognizes viral double-stranded RNA and TLR9 which recognizes CpG DNA motifs, found commonly in both viruses and bacteria. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis and asthma. There is therefore great interest in targeting TLRs therapeutically since blocking TLRs will result in a decrease in the production of inflammatory mediators such as TNF. This volume covers our current understanding of TLRs, and their role in inflammation. Given the primacy of TLRs in the inflammatory process and their emerging role in inflammatory diseases the book is of great interest to researchers working in inflammation and immunology.
Detail Book of Toll like Receptors in Inflammation PDF
- Author : Luke A.J. O'Neill
- Release : 16 March 2006
- Publisher : Springer Science & Business Media
- ISBN : 9783764374419
- Genre : Medical
- Total Page : 254 pages
- Language : English
- PDF File Size : 9,8 Mb
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