The Role of Toll Like Receptor 4 in Infectious and Non Infectious Inflammation is popular PDF and ePub book, written by Carlo Rossetti in 2020-10-30, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, The Role of Toll Like Receptor 4 in Infectious and Non Infectious Inflammation can be Read Online from any device for your convenience.
The Role of Toll Like Receptor 4 in Infectious and Non Infectious Inflammation Book PDF Summary
TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer’s diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis and neuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.
Detail Book of The Role of Toll Like Receptor 4 in Infectious and Non Infectious Inflammation PDF
- Author : Carlo Rossetti
- Release : 30 October 2020
- Publisher : Springer Nature
- ISBN : 9783030563196
- Genre : Science
- Total Page : 180 pages
- Language : English
- PDF File Size : 17,6 Mb
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