The Polymerase Chain Reaction is popular PDF and ePub book, written by Kary B. Mullis in 2012-02-02, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, The Polymerase Chain Reaction can be Read Online from any device for your convenience.
The Polymerase Chain Reaction Book PDF Summary
James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. "It has not escaped our notice," Francis wrote, "that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act ". . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before" and, moreover, " ...
Detail Book of The Polymerase Chain Reaction PDF
- Author : Kary B. Mullis
- Release : 02 February 2012
- Publisher : Springer Science & Business Media
- ISBN : 9781461202578
- Genre : Medical
- Total Page : 464 pages
- Language : English
- PDF File Size : 16,9 Mb
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