Restriction Endonucleases is popular PDF and ePub book, written by Alfred Pingoud in 2012-12-06, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Restriction Endonucleases can be Read Online from any device for your convenience.
Restriction Endonucleases Book PDF Summary
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
Detail Book of Restriction Endonucleases PDF
- Author : Alfred Pingoud
- Release : 06 December 2012
- Publisher : Springer Science & Business Media
- ISBN : 9783642188510
- Genre : Science
- Total Page : 462 pages
- Language : English
- PDF File Size : 8,6 Mb
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