Resistance of Cancer Cells to CTL Mediated Immunotherapy is popular PDF and ePub book, written by Benjamin Bonavida in 2015-06-20, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Resistance of Cancer Cells to CTL Mediated Immunotherapy can be Read Online from any device for your convenience.
Resistance of Cancer Cells to CTL Mediated Immunotherapy Book PDF Summary
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
Detail Book of Resistance of Cancer Cells to CTL Mediated Immunotherapy PDF
- Author : Benjamin Bonavida
- Release : 20 June 2015
- Publisher : Springer
- ISBN : 9783319178073
- Genre : Medical
- Total Page : 364 pages
- Language : English
- PDF File Size : 10,7 Mb
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