Cancer Stem Cell Resistance to Targeted Therapy is popular PDF and ePub book, written by Cristina Maccalli in 2019-06-04, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Cancer Stem Cell Resistance to Targeted Therapy can be Read Online from any device for your convenience.
Cancer Stem Cell Resistance to Targeted Therapy Book PDF Summary
This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.
Detail Book of Cancer Stem Cell Resistance to Targeted Therapy PDF
- Author : Cristina Maccalli
- Release : 04 June 2019
- Publisher : Springer
- ISBN : 9783030166243
- Genre : Medical
- Total Page : 256 pages
- Language : English
- PDF File Size : 8,5 Mb
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