RAS Past Present and Future is popular PDF and ePub book, written by Anonim in 2022-01-29, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, RAS Past Present and Future can be Read Online from any device for your convenience.
RAS Past Present and Future Book PDF Summary
Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once “undruggable RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers. Overview of the history and development of efforts to pharmacologically inhibit RAS. Discussion of the biochemistry and biology of different RAS mutant proteins and how this might be effectively leveraged in the development of anti-RAS therapies. Up-to-date reviews of the cutting-edge approaches to develop new anti-RAS pharmacologics.
Detail Book of RAS Past Present and Future PDF
- Author : Anonim
- Release : 29 January 2022
- Publisher : Academic Press
- ISBN : 9780128244869
- Genre : Science
- Total Page : 358 pages
- Language : English
- PDF File Size : 8,8 Mb
If you're still pondering over how to secure a PDF or EPUB version of the book RAS Past Present and Future by Anonim, don't worry! All you have to do is click the 'Get Book' buttons below to kick off your Download or Read Online journey. Just a friendly reminder: we don't upload or host the files ourselves.