Dynemicin A Uncialamycin and Analogues is popular PDF and ePub book, written by Daniel Best in 2016-06-14, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Dynemicin A Uncialamycin and Analogues can be Read Online from any device for your convenience.
Dynemicin A Uncialamycin and Analogues Book PDF Summary
Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs. Presents two natural ènediynes with similar structures whose total syntheses have been accomplished Explores structural analogs of preparation for purposes of optimizing the anti-cancer activity Describes the total syntheses of dynemicin A, the uncialamycine, as well as analogs by emphasizing the synthesis strategies adopted Features studies of the biological activities and data to bring out the structural elements of these essential compounds
Detail Book of Dynemicin A Uncialamycin and Analogues PDF
- Author : Daniel Best
- Release : 14 June 2016
- Publisher : Elsevier
- ISBN : 9780081010860
- Genre : Medical
- Total Page : 146 pages
- Language : English
- PDF File Size : 21,7 Mb
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