Clinical Trial Optimization Using R is popular PDF and ePub book, written by Alex Dmitrienko in 2017-08-10, it is a fantastic choice for those who relish reading online the Mathematics genre. Let's immerse ourselves in this engaging Mathematics book by exploring the summary and details provided below. Remember, Clinical Trial Optimization Using R can be Read Online from any device for your convenience.
Clinical Trial Optimization Using R Book PDF Summary
Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as supportive R tools, to evaluate and select among simultaneous competing designs or analysis options. It is applicable broadly to statisticians and other quantitative clinical trialists, who have an interest in optimizing clinical trials, clinical trial programs, or associated analytics and decision making. This book presents in depth the Clinical Scenario Evaluation (CSE) framework, and discusses optimization strategies, including the quantitative assessment of tradeoffs. A variety of common development challenges are evaluated as case studies, and used to show how this framework both simplifies and optimizes strategy selection. Specific settings include optimizing adaptive designs, multiplicity and subgroup analysis strategies, and overall development decision-making criteria around Go/No-Go. After this book, the reader will be equipped to extend the CSE framework to their particular development challenges as well.
Detail Book of Clinical Trial Optimization Using R PDF
- Author : Alex Dmitrienko
- Release : 10 August 2017
- Publisher : CRC Press
- ISBN : 9781498735087
- Genre : Mathematics
- Total Page : 319 pages
- Language : English
- PDF File Size : 14,8 Mb
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