Caveolins and Caveolae is popular PDF and ePub book, written by Jean-François Jasmin in 2012-03-12, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Caveolins and Caveolae can be Read Online from any device for your convenience.
Caveolins and Caveolae Book PDF Summary
Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membrane, fully-invaginated caveolae, grape-like clusters of interconnected caveolae (caveosome), or as transcellular channels as a consequence of the fusion of individual caveolae. The caveolin gene family consists of three distinct members, namely Cav-1, Cav-2 and Cav-3. Cav-1 and Cav-2 proteins are usually co-expressed and particularly abundant in epithelial, endothelial, and smooth muscle cells as well as adipocytes and fibroblasts. On the other hand, the Cav-3 protein appears to be muscle-specific and is therefore only expressed in smooth, skeletal and cardiac muscles. Caveolin proteins form high molecular weight homo- and/or hetero-oligomers and assume an unusual topology with both their N- and C-terminal domains facing the cytoplasm.
Detail Book of Caveolins and Caveolae PDF
- Author : Jean-François Jasmin
- Release : 12 March 2012
- Publisher : Springer Science & Business Media
- ISBN : 9781461412229
- Genre : Medical
- Total Page : 199 pages
- Language : English
- PDF File Size : 16,6 Mb
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