ABC Transporters and Multidrug Resistance is popular PDF and ePub book, written by Ahcène Boumendjel in 2009-06-17, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, ABC Transporters and Multidrug Resistance can be Read Online from any device for your convenience.
ABC Transporters and Multidrug Resistance Book PDF Summary
A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.
Detail Book of ABC Transporters and Multidrug Resistance PDF
- Author : Ahcène Boumendjel
- Release : 17 June 2009
- Publisher : John Wiley & Sons
- ISBN : 9780470495124
- Genre : Medical
- Total Page : 475 pages
- Language : English
- PDF File Size : 18,7 Mb
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