What is the Clinical Implication of Whole Blood Viscosity in Cardio Vascular Medicine is popular PDF and ePub book, written by Dr.Hakim Saboowala. in 2019-10-09, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, What is the Clinical Implication of Whole Blood Viscosity in Cardio Vascular Medicine can be Read Online from any device for your convenience.
What is the Clinical Implication of Whole Blood Viscosity in Cardio Vascular Medicine Book PDF Summary
Whole blood is a non-Newtonian fluid (A non-Newtonian fluid is a fluid that does not follow Newton's law of viscosity, i.e. constant viscosity independent of stress.), which means that its viscosity depends on shear rate. [Shear Rate: Shear rate is the rate of change of velocity at which one layer of fluid passes over an adjacent layer e.g. consider that a fluid is placed between two parallel plates that are 1.0 cm apart, the upper plate moving at a velocity of 1.0 cm/sec and the lower plate fixed.] At low shear, blood cells aggregate, which induces a sharp increase in viscosity, whereas at higher shear blood cells disaggregate, deform and align in the direction of flow. Other important determinants of blood viscosity are: · The Haematocrit, · The presence of Macromolecules in the medium, · Temperature and, · The deformability of Red blood cells (at high shear). At the sites of severe atherosclerotic obstructions or at vasospastic locations, when change of vessel diameter is limited, blood viscosity contributes to stenotic resistance thereby jeopardizing tissue perfusion. However, blood viscosity plays its most important role in the microcirculation where it contributes significantly to peripheral resistance and may cause sludging in the postcapillary venules. Apart from the direct haemodynamic significance, an increase in blood viscosity at low shear by red blood cell aggregation is also associated with increased thrombotic risk, as has been demonstrated in atrial fibrillation. Furthermore, as increased red blood cell aggregation is a reflection of inflammation, hyperviscosity has been shown to be a marker of inflammatory activity. Thus, because of its potential role in haemodynamics, thrombosis and inflammation, it has been attempted in this Booklet to emphasize the determination of the whole blood viscosity as it could provide useful information for diagnostics and therapy of(cardio)vascular disease. ……Dr.H.K.Saboowala.
Detail Book of What is the Clinical Implication of Whole Blood Viscosity in Cardio Vascular Medicine PDF
- Author : Dr.Hakim Saboowala.
- Release : 09 October 2019
- Publisher : Dr.Hakim Saboowala
- ISBN : 978186723xxxx
- Genre : Medical
- Total Page : 30 pages
- Language : English
- PDF File Size : 14,8 Mb
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