Vesicle Trafficking in Cancer is popular PDF and ePub book, written by Yosef Yarden in 2013-04-02, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Vesicle Trafficking in Cancer can be Read Online from any device for your convenience.
Vesicle Trafficking in Cancer Book PDF Summary
Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.
Detail Book of Vesicle Trafficking in Cancer PDF
- Author : Yosef Yarden
- Release : 02 April 2013
- Publisher : Springer Science & Business Media
- ISBN : 9781461465287
- Genre : Medical
- Total Page : 402 pages
- Language : English
- PDF File Size : 21,5 Mb
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