Tumor Metabolome Targeting and Drug Development is popular PDF and ePub book, written by Steven Kanner in 2014-01-07, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Tumor Metabolome Targeting and Drug Development can be Read Online from any device for your convenience.
Tumor Metabolome Targeting and Drug Development Book PDF Summary
In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism. The metabolic network in cells promotes the generation of both energy and biomass needed for them to grow, divide and differentiate. However, the metabolism of malignant cells generally varies from that of normal cells. These differences provide a platform for the discovery of new approaches to targeting potential vulnerabilities in cancer cells for therapeutic options Some of the significant changes that occur involve ATP production and consumption that modulates the ATP to ADP ratio, hypoxia and the effects of reactive oxygen species on glycolysis, regulation of mitochondrial respiration, induction and suppression of autophagy, and the Warburg effect and “reverse” Warburg effect--these topics and more are discussed in this volume.
Detail Book of Tumor Metabolome Targeting and Drug Development PDF
- Author : Steven Kanner
- Release : 07 January 2014
- Publisher : Springer Science & Business Media
- ISBN : 9781461495451
- Genre : Medical
- Total Page : 348 pages
- Language : English
- PDF File Size : 7,8 Mb
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