Translational Research Methods in Diabetes Obesity and Nonalcoholic Fatty Liver Disease is popular PDF and ePub book, written by Andrew J. Krentz in 2019-04-02, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Translational Research Methods in Diabetes Obesity and Nonalcoholic Fatty Liver Disease can be Read Online from any device for your convenience.
Translational Research Methods in Diabetes Obesity and Nonalcoholic Fatty Liver Disease Book PDF Summary
This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs. This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development. Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.
Detail Book of Translational Research Methods in Diabetes Obesity and Nonalcoholic Fatty Liver Disease PDF
- Author : Andrew J. Krentz
- Release : 02 April 2019
- Publisher : Springer
- ISBN : 9783030117481
- Genre : Medical
- Total Page : 556 pages
- Language : English
- PDF File Size : 13,9 Mb
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