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Therapeutics for Ebola virus disease 19 August 2022 Book PDF Summary

Ebola virus disease (EVD) is a life-threatening disease caused by Ebola virus (EBOV; Zaire ebolavirus). Viruses of the genus Ebolavirus (of the family Filoviridae) can cause life-threatening disease. EBOV causes outbreaks of EVD, historically the most severe and most frequent. This guidance, due to the evidence available, is directed only to the treatment of EVD, the disease caused by EBOV (Zaire ebolavirus). During early EVD, patients present with a non-specific febrile illness, followed by gastrointestinal signs and symptoms that frequently lead to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. EVD case fatality remains high, with a pooled case fatality rate of 60% (95% confidence interval [CI]: 47–73%) in outbreaks from 2010–2020. Following the publication of an RCT demonstrating superior efficacy of two EVD therapeutics, in comparison to the ZMapp control arm, WHO proposed to develop a new guideline. This is a new guideline written to accompany the optimized supportive care (oSoC) for EVD standard operating procedures. The guideline aims to summarize high quality evidence for EVD therapeutics and make recommendations for their use.

Detail Book of Therapeutics for Ebola virus disease 19 August 2022 PDF

Therapeutics for Ebola virus disease  19 August 2022
  • Author : Anonim
  • Release : 19 August 2022
  • Publisher : World Health Organization
  • ISBN : 9789240055742
  • Genre : Medical
  • Total Page : 44 pages
  • Language : English
  • PDF File Size : 11,6 Mb

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