Targeting the Wnt Pathway in Cancer is popular PDF and ePub book, written by Kathleen H. Goss in 2011-01-25, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Targeting the Wnt Pathway in Cancer can be Read Online from any device for your convenience.
Targeting the Wnt Pathway in Cancer Book PDF Summary
Inappropriate activation of the Wnt signaling pathway is observed in many human cancers and is sufficient to drive tumor initiation and progression in numerous contexts. Multiple mechanisms, such as overexpression of Wnt ligands, inactivation of the APC and Axin tumor suppressors, and mutation of -catenin, are responsible for pathway activation in tumor cells. The development of potent Wnt pathway antagonists for therapeutic use has been a major effort for investigators in both academia and industry in recent years. This book will provide an overview of the Wnt pathway as a therapeutic target for cancer, and discuss the preclinical development of inhibitors specifically directed to upstream and downstream components of the pathway.
Detail Book of Targeting the Wnt Pathway in Cancer PDF
- Author : Kathleen H. Goss
- Release : 25 January 2011
- Publisher : Springer Science & Business Media
- ISBN : 9781441980236
- Genre : Medical
- Total Page : 249 pages
- Language : English
- PDF File Size : 19,5 Mb
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