Sphingolipids and Metabolic Disease is popular PDF and ePub book, written by L. Ashley Cowart in 2011-09-15, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Sphingolipids and Metabolic Disease can be Read Online from any device for your convenience.
Sphingolipids and Metabolic Disease Book PDF Summary
Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological outcomes of metabolic disease including insulin resistance, inflammation, cardiomyopathy, and others. This volume addresses not only the fundamentals of sphingolipid metabolism and analysis, but also the roles of sphingolipids in these disease processes.
Detail Book of Sphingolipids and Metabolic Disease PDF
- Author : L. Ashley Cowart
- Release : 15 September 2011
- Publisher : Springer Science & Business Media
- ISBN : 9781461406501
- Genre : Science
- Total Page : 163 pages
- Language : English
- PDF File Size : 17,5 Mb
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