Rho Gtpases Molecular Biology In Health And Disease is popular PDF and ePub book, written by Philippe Fort in 2017-12-12, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Rho Gtpases Molecular Biology In Health And Disease can be Read Online from any device for your convenience.
Rho Gtpases Molecular Biology In Health And Disease Book PDF Summary
Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progression or apoptosis. In view of such pleiotropic activities, Rho-controlled signaling has proven to be of medical relevance, especially in tumorigenesis, disease-associated bone remodeling and infectiology.This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis.This updated review on the biology of Rho GTPases is an essential read for molecular and cell biologists. It is also an invaluable guide to post-graduate and medical students who wish to deepen their knowledge in cell biology.
Detail Book of Rho Gtpases Molecular Biology In Health And Disease PDF
- Author : Philippe Fort
- Release : 12 December 2017
- Publisher : World Scientific
- ISBN : 9789813228801
- Genre : Science
- Total Page : 213 pages
- Language : English
- PDF File Size : 20,7 Mb
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