Protein Allostery in Drug Discovery is popular PDF and ePub book, written by Jian Zhang in 2019-11-09, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Protein Allostery in Drug Discovery can be Read Online from any device for your convenience.
Protein Allostery in Drug Discovery Book PDF Summary
The book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes and controls physiological activities. Allostery can both cause human diseases and contribute to development of new therapeutics. Allosteric drugs exhibit unparalleled advantages compared to conventional orthosteric drugs, rendering the development of allosteric modulators as an appealing strategy to improve selectivity and pharmacodynamic properties in drug leads. The Series delineates the immense significance of protein allostery—as demonstrated by recent advances in the repertoires of the concept, its mechanistic mechanisms, and networks, characteristics of allosteric proteins, modulators, and sites, development of computational and experimental methods to predict allosteric sites, small-molecule allosteric modulators of protein kinases and G-protein coupled receptors, engineering allostery, and the underlying role of allostery in precise medicine. Comprehensive understanding of protein allostery is expected to guide the rational design of allosteric drugs for the treatment of human diseases. The book would be useful for scientists and students in the field of protein science and Pharmacology etc.
Detail Book of Protein Allostery in Drug Discovery PDF
- Author : Jian Zhang
- Release : 09 November 2019
- Publisher : Springer Nature
- ISBN : 9789811387197
- Genre : Medical
- Total Page : 384 pages
- Language : English
- PDF File Size : 17,6 Mb
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