PRINS and In Situ PCR Protocols is popular PDF and ePub book, written by Franck Pellestor in 2008-02-03, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, PRINS and In Situ PCR Protocols can be Read Online from any device for your convenience.
PRINS and In Situ PCR Protocols Book PDF Summary
The in situ hybridization and PCR technologies are now well-established molecular techniques for studying chromosomal aneuploidy and rearran- ments, gene localization and expression, and genomic organization. Over the last decade, we have seen increasing applications in these fields. By combining the high sensitivity of the PCR reaction and the cytological localization of target sequences, both PRINS and in situ PCR techniques have provided highly powerful complements to FISH for in situ cellular and molecular investigations. Both these approaches have several advantages in terms of sensitivity and specificity, owing to the use of primers and to the fast kinetics of annealing and elongation reactions in situ. In the first edition of PRINS and In Situ PCR Protocols edited by John R. Gosden, experts in the field presented in detail a variety of applications of PRINS and in situ PCR techniques, in a wide range of clinical conditions. Since the publication of this successful reference book, there have been s- nificant improvements in in situ detection techniques. This completely revised and updated second edition presents a compreh- sive selection of new procedures developed in the field of PRINS and in situ PCR technologies. The book has two sections. Part I, Basic Methodology, contains chapters that provide useful protocols for many variations of PRINS and in situ PCR, including a new fast multicolor PRINS method, and protocols for PRINS detection of unique sequences in situ.
Detail Book of PRINS and In Situ PCR Protocols PDF
- Author : Franck Pellestor
- Release : 03 February 2008
- Publisher : Springer Science & Business Media
- ISBN : 9781597450683
- Genre : Science
- Total Page : 257 pages
- Language : English
- PDF File Size : 17,6 Mb
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