Predictive Methods in Percutaneous Absorption is popular PDF and ePub book, written by Gary P. Moss in 2015-07-01, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Predictive Methods in Percutaneous Absorption can be Read Online from any device for your convenience.
Predictive Methods in Percutaneous Absorption Book PDF Summary
This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.
Detail Book of Predictive Methods in Percutaneous Absorption PDF
- Author : Gary P. Moss
- Release : 01 July 2015
- Publisher : Springer
- ISBN : 9783662473719
- Genre : Medical
- Total Page : 206 pages
- Language : English
- PDF File Size : 13,7 Mb
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