Preclinical Evaluation of Antimicrobial Nanodrugs is popular PDF and ePub book, written by Juan Bueno in 2020-05-08, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Preclinical Evaluation of Antimicrobial Nanodrugs can be Read Online from any device for your convenience.
Preclinical Evaluation of Antimicrobial Nanodrugs Book PDF Summary
Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Detail Book of Preclinical Evaluation of Antimicrobial Nanodrugs PDF
- Author : Juan Bueno
- Release : 08 May 2020
- Publisher : Springer Nature
- ISBN : 9783030438555
- Genre : Medical
- Total Page : 125 pages
- Language : English
- PDF File Size : 15,8 Mb
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