PATH Proliferation Accumulation Tumor Hypothesis is popular PDF and ePub book, written by Thomas Wascher in 2018-08-15, it is a fantastic choice for those who relish reading online the Uncategoriezed genre. Let's immerse ourselves in this engaging Uncategoriezed book by exploring the summary and details provided below. Remember, PATH Proliferation Accumulation Tumor Hypothesis can be Read Online from any device for your convenience.
PATH Proliferation Accumulation Tumor Hypothesis Book PDF Summary
What is or what does a gene mutation do? A gene mutation, i.e. the damage of a gene, leads to a gene expressing more, less or modified proteins. These altered proteins alter the behaviour of the cell. And this is how cancer is ultimately to develop: Changed proteins due to changes in the genes. But what would happen if these changes in the proteins were not caused by mutations in the genes, but by direct damage to the proteins? Then the result "cancer" would be the same, but otherwise everything would be different. And cancer could be curable. We cannot reverse a mutation, but we can reverse a mechanical process such as protein accumulation. At least we could considerably influence such a carcinogenesis. The proliferation-accumulation-tumour-hypothesis describes how this might be possible. According to PATH, cancer is not a mutation disease, but a protein accumulation disease. But a protein accumulation (protein oxidation / protein aggregation) in immortal stem cells. And a protein accumulation that affecting 400 protein types (mainly cell cycle proteins) and millions of protein copies simultaneously. A protein accumulation in which autophagocytosis in the G0 phase - as the most important proteolysis factor - is no longer sufficiently effective. PATH is based on the latest findings on the ubiquitin proteasome system, cyclins (in particular Cyclin-D-CDK4,6) and autophagy (according to Ohsumi's findings) and their role in the development of tumours. And PATH also shows why certain forms of treatment and substances (e.g. acetylsalicylic acid [aspirin], metformin, 2-deoxy-2-glucose, methadone, terfenadine, etc.) have a certain effect in studies. And how cancer could possibly be hindered in its development to such an extent that a lethal effect is omitted. For example, PATH also explains better why a person has a 50% chance of developing cancer or at least a 25% chance of dying from it. The most important basis for the development of PATH was the rigorous detachment from the cancer multimutation principle, which has not been effective to date, and the exclusive reorientation towards the most probable and logical facts and conclusions. And the realization: „What is the cause of death for at least 25% of all people cannot be something that has to be caused by a rare, undirected coincidence (mutation).“
Detail Book of PATH Proliferation Accumulation Tumor Hypothesis PDF
- Author : Thomas Wascher
- Release : 15 August 2018
- Publisher : Thomas Wascher
- ISBN : 978186723xxxx
- Genre : Uncategoriezed
- Total Page : 107 pages
- Language : English
- PDF File Size : 21,7 Mb
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