Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC is popular PDF and ePub book, written by Anthony Faber in 2023-01-30, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC can be Read Online from any device for your convenience.
Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC Book PDF Summary
Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer. Presents historical context on how NSCLC and SCLC has been treated, with an emphasis on NSCLC and how the concept of EGFR inhibitors has been implemented Discusses critical resistant mechanisms seen in the clinic to 1st, 2nd and 3rd generation EGFR inhibitors Encompasses the current state of affairs in clinical trials to address resistance
Detail Book of Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC PDF
- Author : Anthony Faber
- Release : 30 January 2023
- Publisher : Academic Press
- ISBN : 9780128228340
- Genre : Science
- Total Page : 150 pages
- Language : English
- PDF File Size : 17,8 Mb
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