Optimal Control of Drug Administration in Cancer Chemotherapy is popular PDF and ePub book, written by Rory Martin in 1994, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Optimal Control of Drug Administration in Cancer Chemotherapy can be Read Online from any device for your convenience.
Optimal Control of Drug Administration in Cancer Chemotherapy Book PDF Summary
This monograph is a study of optimal control applied to cancer chemotherapy, the treatment of cancer using drugs that kill cancer cells. The aim is to determine whether current methods for the administration of chemotherapy are optimal, and if alternative regimens should be considered.The research utilizes the mathematical theory of optimal control, an active research area for many mathematicians, scientists, and engineers. It is of multidisciplinary nature, having been applied to areas ranging from engineering to biomedicine. The aim in optimal control is to achieve a given objective at minimum cost. A set of differential equations is used to describe the evolution in time of the process being modelled, and constraints limit the policies that can be used to attain the objective.In this monograph, mathematical models are used to construct optimal drug schedules. These are treatment guidelines specifying which drug to deliver, when, and at what dose. Many current drug schedules have been derived empirically, based upon ?rules of thumb?.The monograph has been structured so that most of the high-level mathematics is introduced in a special appendix. In this way, a scientist can skip the more subtle aspects of the theory and still understand the biomedical applications that follow. However, the text is self-contained so that a deeper understanding of the mathematics of optimal control can be gained from the mathematical appendix.The mathematical models in this book and the associated computer simulations show that low intensity chemotherapy is a better choice of treatment than high intensity chemotherapy, under certain conditions.
Detail Book of Optimal Control of Drug Administration in Cancer Chemotherapy PDF
- Author : Rory Martin
- Release : 20 September 1994
- Publisher : World Scientific
- ISBN : 9789810214289
- Genre : Medical
- Total Page : 202 pages
- Language : English
- PDF File Size : 17,9 Mb
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