OECD Guidelines for the Testing of Chemicals Section 4 Test No 495 Ros Reactive Oxygen Species Assay for Photoreactivity is popular PDF and ePub book, written by OECD in 2019-06-18, it is a fantastic choice for those who relish reading online the Uncategoriezed genre. Let's immerse ourselves in this engaging Uncategoriezed book by exploring the summary and details provided below. Remember, OECD Guidelines for the Testing of Chemicals Section 4 Test No 495 Ros Reactive Oxygen Species Assay for Photoreactivity can be Read Online from any device for your convenience.
OECD Guidelines for the Testing of Chemicals Section 4 Test No 495 Ros Reactive Oxygen Species Assay for Photoreactivity Book PDF Summary
Phototoxicity is defined as a toxic response is elicited by topically or systemically administered photoreactive chemicals after the exposure of the body to environmental light. Several classes of photoreactive chemicals could cause phototoxic reactions when activated by light at otherwise non-toxic doses. Phototoxicity can be categorized as photoirritation, photoallergy, and photogenotoxicity. The purpose of this test is to measure the phototoxicity of a chemical. The main event in any phototoxic reaction is the absorption of photons of a wavelength that induces the excitation of the chromophore. Excitation energy is often transferred to oxygen molecules, followed by the generation of ROS (reactive Oxygen Species). Measurements are performed using a spectrometer. The determination of the ROS generation from irradiated chemicals with simulated sunlight is indicative of phototoxic potential.
Detail Book of OECD Guidelines for the Testing of Chemicals Section 4 Test No 495 Ros Reactive Oxygen Species Assay for Photoreactivity PDF
- Author : OECD
- Release : 18 June 2019
- Publisher : OECD Publishing
- ISBN : 9789264567115
- Genre : Uncategoriezed
- Total Page : 18 pages
- Language : English
- PDF File Size : 16,5 Mb
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