Molecular Targets in Protein Misfolding and Neurodegenerative Disease is popular PDF and ePub book, written by Pierfausto Seneci in 2014-10-07, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Molecular Targets in Protein Misfolding and Neurodegenerative Disease can be Read Online from any device for your convenience.
Molecular Targets in Protein Misfolding and Neurodegenerative Disease Book PDF Summary
Aimed at "drug discoverers" – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases Provides a “drug discovery” application oriented perspective, evaluating targets and candidates for their overall therapeutic potential Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets
Detail Book of Molecular Targets in Protein Misfolding and Neurodegenerative Disease PDF
- Author : Pierfausto Seneci
- Release : 07 October 2014
- Publisher : Academic Press
- ISBN : 9780128004999
- Genre : Science
- Total Page : 314 pages
- Language : English
- PDF File Size : 13,9 Mb
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