Molecular Genetics of Dysregulated pH Homeostasis is popular PDF and ePub book, written by Jen-Tsan Ashley Chi in 2014-10-20, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Molecular Genetics of Dysregulated pH Homeostasis can be Read Online from any device for your convenience.
Molecular Genetics of Dysregulated pH Homeostasis Book PDF Summary
Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
Detail Book of Molecular Genetics of Dysregulated pH Homeostasis PDF
- Author : Jen-Tsan Ashley Chi
- Release : 20 October 2014
- Publisher : Springer
- ISBN : 9781493916832
- Genre : Medical
- Total Page : 158 pages
- Language : English
- PDF File Size : 8,9 Mb
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