MIPs and Their Roles in the Exchange of Metalloids is popular PDF and ePub book, written by Thomas P. Jahn in 2011-01-11, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, MIPs and Their Roles in the Exchange of Metalloids can be Read Online from any device for your convenience.
MIPs and Their Roles in the Exchange of Metalloids Book PDF Summary
Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subsequent years of research showed that the water channel AQP1 was only the tip of an iceberg; the iceberg itself being the ubiquitous super family of membrane intrinsic proteins (MIPs) that facilitate trans-membrane transport of water and an increasing number of small, water-soluble and uncharged compounds. Here we introduce you to the superfamily of MIPs and provide a summary about our gradually refined understanding of the phylogenetic relationship of its members. This volume is dedicated to the metalloids, a recently discovered group of substrates for a number of specific MIPs in a diverse spectrum of organisms. Particular focus is given to the essential boron, the beneficial silicon and the highly toxic arsenic. The respective MIP isoforms that facilitate the transport of these metalloids include members from several clades of the phylogenetic tree, suggesting that metalloid transport is an ancient function within this family of channel proteins. Among all the various substrates that have been shown to be transported by MIPs, metalloids take an outstanding position. While water transport seems to be a common function of many MIPs, single isoforms in plants have been identified as being crucially important for the uptake of boric acid as well as silicic acid. Here, the function seems not to be redundant, as mutations in those genes render plants deficient in boron and silicon, respectively.
Detail Book of MIPs and Their Roles in the Exchange of Metalloids PDF
- Author : Thomas P. Jahn
- Release : 11 January 2011
- Publisher : Springer Science & Business Media
- ISBN : 9781441963154
- Genre : Medical
- Total Page : 158 pages
- Language : English
- PDF File Size : 13,5 Mb
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