Innate Immune Regulation and Cancer Immunotherapy is popular PDF and ePub book, written by Rong-Fu Wang in 2012-02-02, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Innate Immune Regulation and Cancer Immunotherapy can be Read Online from any device for your convenience.
Innate Immune Regulation and Cancer Immunotherapy Book PDF Summary
Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in various types of cancers and suppress antitumor immunity. Furthermore, tumor-specific Treg cells can inhibit immune responses only when they are exposed to antigens presented by tumor cells. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer.
Detail Book of Innate Immune Regulation and Cancer Immunotherapy PDF
- Author : Rong-Fu Wang
- Release : 02 February 2012
- Publisher : Springer Science & Business Media
- ISBN : 9781441999146
- Genre : Medical
- Total Page : 476 pages
- Language : English
- PDF File Size : 20,9 Mb
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