Inflammation and Angiogenesis is popular PDF and ePub book, written by Domenico Ribatti in 2017-11-08, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Inflammation and Angiogenesis can be Read Online from any device for your convenience.
Inflammation and Angiogenesis Book PDF Summary
This book is focused on the analysis of the role played by immune cell components in the angiogenic process associated with inflammation and tumor growth. Both innate and adaptive immune cells are involved in the mechanisms of endothelial cell proliferation, migration and activation, through the production and release of a large spectrum of pro-angiogenic mediators. These may create the specific microenvironment that favors an increased rate of tissue vascularization. The link between chronic inflammation and tumorigenesis was first proposed by Rudolf Virchow in 1863 after the observation that infiltrating leukocytes are a hallmark of tumors and first established a causative connection between the lymph reticular infiltrate at sites of chronic inflammation and the development of cancer. Tumors were described as wounds that never heal and surgeons have long described the tendency of tumors to recur in healing resection margin and it has been reported that wound healing environment provides an opportunistic matrix for tumor growth. As angiogenesis is the result of a net balance between the activities exerted by positive and negative regulators, this book will also provide information on some anti-angiogenic properties of immune cells that may be utilized for a potential pharmacological use as anti-angiogenic agents in inflammation as well as in cancer. The work is written for researchers in the field and also for graduate students which approach this matter.
Detail Book of Inflammation and Angiogenesis PDF
- Author : Domenico Ribatti
- Release : 08 November 2017
- Publisher : Springer
- ISBN : 9783319684482
- Genre : Medical
- Total Page : 116 pages
- Language : English
- PDF File Size : 13,6 Mb
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