Inducing Targeted Protein Degradation is popular PDF and ePub book, written by Philipp Cromm in 2022-11-15, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Inducing Targeted Protein Degradation can be Read Online from any device for your convenience.
Inducing Targeted Protein Degradation Book PDF Summary
Inducing Targeted Protein Degradation Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation Since the breakthrough of the PROTAC technology in 2015, targeted protein degradation has revolutionized drug discovery, enabling pharma companies to develop completely novel therapeutics. Inducing Targeted Protein Degradation is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the druggable space. In Inducing Targeted Protein Degradation, readers will find the most recent information on: Cellular mechanisms of targeted protein degradation and current approaches to utilize these mechanisms for drug discovery A comparison of different induced degradation approaches, including PROTAC, molecular glues, LYTACs and ATTECs as well as additional post translational modifications Drug development aspects such as DMPK optimization and criteria for the selection of clinical candidates A discussion of the potential of targeted degradation for expanding the druggable space Inducing Targeted Protein Degradation will serve as a practice-oriented reference on induced protein degradation for drug discovery professionals and for researchers employing chemical biology approaches.
Detail Book of Inducing Targeted Protein Degradation PDF
- Author : Philipp Cromm
- Release : 15 November 2022
- Publisher : John Wiley & Sons
- ISBN : 9783527836215
- Genre : Medical
- Total Page : 389 pages
- Language : English
- PDF File Size : 17,8 Mb
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