Filaggrin is popular PDF and ePub book, written by Jacob P. Thyssen in 2014-05-27, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Filaggrin can be Read Online from any device for your convenience.
Filaggrin Book PDF Summary
Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major predisposing factors for related asthma and hay fever. This textbook provides comprehensive and detailed coverage of the effects of FLG mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
Detail Book of Filaggrin PDF
- Author : Jacob P. Thyssen
- Release : 27 May 2014
- Publisher : Springer
- ISBN : 9783642543791
- Genre : Medical
- Total Page : 362 pages
- Language : English
- PDF File Size : 9,6 Mb
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