Fast Facts EGFR Exon 20 Insertion Mutations in NSCLC is popular PDF and ePub book, written by Julia Rotow in 2022-06-30, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Fast Facts EGFR Exon 20 Insertion Mutations in NSCLC can be Read Online from any device for your convenience.
Fast Facts EGFR Exon 20 Insertion Mutations in NSCLC Book PDF Summary
Lung cancer is still a major cause of death globally, but the development of personalized, precision medicine has had a marked effect on treatment management and improved clinical outcomes, particularly for those with advanced stage non-small-cell lung cancer (NSCLC). EGFR mutations are the third most common mutation found in patients with advanced stage NSCLC. First-line treatment with a traditional epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is indicated for most patients, but not for patients with EGFR exon 20 insertion mutations (ex20ins). Instead, recent approvals of an EGFR ex20ins-specific TKI (mobocertinib) and a bispecific antibody (amivantamab) targeting both EGFR and mesenchymalepithelial transition factor (MET) offer the potential for improved outcomes in this patient population. Furthermore, new approaches to treatment continue to be developed and trials for new agents with greater activity against ex20ins mutations are ongoing. Table of Contents: • EGFR and mutations • EGFR mutation testing • Treatment decisions • Therapies in development
Detail Book of Fast Facts EGFR Exon 20 Insertion Mutations in NSCLC PDF
- Author : Julia Rotow
- Release : 30 June 2022
- Publisher : Karger Medical and Scientific Publishers
- ISBN : 9783318070200
- Genre : Medical
- Total Page : 62 pages
- Language : English
- PDF File Size : 12,9 Mb
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