Clinical Epigenetics is popular PDF and ePub book, written by Luke B. Hesson in 2019-08-31, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Clinical Epigenetics can be Read Online from any device for your convenience.
Clinical Epigenetics Book PDF Summary
In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of pioneers who have helped shape these fields. The various mechanisms by which epigenetics can regulate the function of the genome is described. These include DNA methylation, histone modifications, histone variants, nucleosome positioning, cis-regulatory elements, non-coding RNAs and the three-dimensional organisation of chromatin in the nucleus. These are discussed in the context of embryological development, cancer and imprinting disorders, and include examples of epigenetic changes that can be used in diagnosis, prediction of therapeutic response, prognostication or disease monitoring. Finally, for those wishing to implement epigenetic testing in a diagnostic setting, the book includes a case study that illustrates the clinical utility of epigenetic testing.
Detail Book of Clinical Epigenetics PDF
- Author : Luke B. Hesson
- Release : 31 August 2019
- Publisher : Springer Nature
- ISBN : 9789811389580
- Genre : Medical
- Total Page : 265 pages
- Language : English
- PDF File Size : 13,8 Mb
If you're still pondering over how to secure a PDF or EPUB version of the book Clinical Epigenetics by Luke B. Hesson, don't worry! All you have to do is click the 'Get Book' buttons below to kick off your Download or Read Online journey. Just a friendly reminder: we don't upload or host the files ourselves.