Clinical Benefits of Leukodepleted Blood Products is popular PDF and ePub book, written by Joseph Sweeney in 2013-06-29, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Clinical Benefits of Leukodepleted Blood Products can be Read Online from any device for your convenience.
Clinical Benefits of Leukodepleted Blood Products Book PDF Summary
Joseph Sweeney, Andrew Heaton he presence of allogeneic leukocytes in blood products received little T attention until the mid-1950s when these "passenger" cells were im plicated in the etiology of febrile transfusion reactions, and early strate gies based on centrifugation were developed to effect their removal. In recent decades and, particularly in the past five years, there has been an accumulation of literature implicating leukocytes in a wide variety of undesirable reactions to blood transfusion. White cells are the least numerous of the cellular elements in blood and ratios of white cells to platelets and white cells to red cells are ap proximately 1:15 to 1:1000 respectively. This ratio is maintained in whole blood, but may be altered slightly in the process of component prepara tion. Any production or processing step which intentionally decreases this ratio will result in a product which can be described as white cell depleted. It has, however, become more common to define the outcome as a residual white cell content, rather than a decrease in cellular ratios, although the latter makes more sense on theoretical grounds, since deple tion of white cells needs to be put in the context of any unintentional loss of red cells or platelets. The end result of this intentional processing step, therefore, is generally expressed as the residual absolute number of white cells or as the degree of difference in white cell content, the latter expressed as either a percentage change or as a logarithmic reduction.
Detail Book of Clinical Benefits of Leukodepleted Blood Products PDF
- Author : Joseph Sweeney
- Release : 29 June 2013
- Publisher : Springer Science & Business Media
- ISBN : 9783662265383
- Genre : Medical
- Total Page : 202 pages
- Language : English
- PDF File Size : 8,6 Mb
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