Cellular Peptide Hormone Synthesis and Secretory Pathways is popular PDF and ePub book, written by Jens F. Rehfeld in 2010-03-10, it is a fantastic choice for those who relish reading online the Science genre. Let's immerse ourselves in this engaging Science book by exploring the summary and details provided below. Remember, Cellular Peptide Hormone Synthesis and Secretory Pathways can be Read Online from any device for your convenience.
Cellular Peptide Hormone Synthesis and Secretory Pathways Book PDF Summary
The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.
Detail Book of Cellular Peptide Hormone Synthesis and Secretory Pathways PDF
- Author : Jens F. Rehfeld
- Release : 10 March 2010
- Publisher : Springer Science & Business Media
- ISBN : 9783642118364
- Genre : Science
- Total Page : 245 pages
- Language : English
- PDF File Size : 9,6 Mb
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