Cellular and Molecular Mechanisms in Hypertension is popular PDF and ePub book, written by Robert H. Cox in 2013-03-08, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Cellular and Molecular Mechanisms in Hypertension can be Read Online from any device for your convenience.

Cellular and Molecular Mechanisms in Hypertension Book PDF Summary

Hypertension is recognized to be one of the major risk factors for the development of peripheral vascular disease. The last decade has witnessed several major advances in therapy for hypertension, including the development of angiotensin-converting enzyme inhibitors and calcium channel blockers. These compounds have greatly improved the ability to control blood pressure and to reduce the impact of this risk factor on morbidity and mortality. In spite of these advances, cardiovascular disease remains a major health problem in most modern industrialized countries with related deaths exceeding those from all other causes combined. In contrast to these advances in therapy, our understanding of the basic mechanisms responsible for the pathogenesis of hypertension remains incomplete. Recent studies have produced new insights into the nature of the regulation of muscle contraction in both heart and blood vessels as well as the changes in muscle function that occur in hypertension. However, the effects of antihypertensive therapy, both in terms of restoring normal function and in producing reversal of hypertension-associated changes, has not been as thoroughly studied, especially in the vasculature. Studies in the heart suggest that the efficacy of different therapeutic agents in restoring normal function and reversing hypertensive changes vary substantially with the mechanism of action of the therapeutic agent. It has also been recently determined that some therapeutic agents produce adverse effects on plasma lipid profiles, which could lead to the secondary acceleration of the atherosclerotic process, while at the same time normalizing blood pressure.

Detail Book of Cellular and Molecular Mechanisms in Hypertension PDF

Cellular and Molecular Mechanisms in Hypertension
  • Author : Robert H. Cox
  • Release : 08 March 2013
  • Publisher : Springer Science & Business Media
  • ISBN : 9781468460155
  • Genre : Medical
  • Total Page : 245 pages
  • Language : English
  • PDF File Size : 13,7 Mb

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