Catalytically Active Nucleic Acids is popular PDF and ePub book, written by Harald Seitz in 2019-09-30, it is a fantastic choice for those who relish reading online the Technology & Engineering genre. Let's immerse ourselves in this engaging Technology & Engineering book by exploring the summary and details provided below. Remember, Catalytically Active Nucleic Acids can be Read Online from any device for your convenience.
Catalytically Active Nucleic Acids Book PDF Summary
This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids’ fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes. After the discovery of natural ribozymes – RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds – numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat. Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area.
Detail Book of Catalytically Active Nucleic Acids PDF
- Author : Harald Seitz
- Release : 30 September 2019
- Publisher : Springer Nature
- ISBN : 9783030296469
- Genre : Technology & Engineering
- Total Page : 123 pages
- Language : English
- PDF File Size : 9,8 Mb
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