Cancer Cell Lines Part 2 is popular PDF and ePub book, written by John Masters in 2006-04-11, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Cancer Cell Lines Part 2 can be Read Online from any device for your convenience.
Cancer Cell Lines Part 2 Book PDF Summary
Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions offundamental importance to the relevanceof human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative oftumors at that site is naïve and misleading.
Detail Book of Cancer Cell Lines Part 2 PDF
- Author : John Masters
- Release : 11 April 2006
- Publisher : Springer Science & Business Media
- ISBN : 9780306468612
- Genre : Medical
- Total Page : 376 pages
- Language : English
- PDF File Size : 16,8 Mb
If you're still pondering over how to secure a PDF or EPUB version of the book Cancer Cell Lines Part 2 by John Masters, don't worry! All you have to do is click the 'Get Book' buttons below to kick off your Download or Read Online journey. Just a friendly reminder: we don't upload or host the files ourselves.