Bayesian Designs for Phase I II Clinical Trials is popular PDF and ePub book, written by Ying Yuan in 2017-12-19, it is a fantastic choice for those who relish reading online the Mathematics genre. Let's immerse ourselves in this engaging Mathematics book by exploring the summary and details provided below. Remember, Bayesian Designs for Phase I II Clinical Trials can be Read Online from any device for your convenience.

Bayesian Designs for Phase I II Clinical Trials Book PDF Summary

Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes. Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.

Detail Book of Bayesian Designs for Phase I II Clinical Trials PDF

Bayesian Designs for Phase I II Clinical Trials
  • Author : Ying Yuan
  • Release : 19 December 2017
  • Publisher : CRC Press
  • ISBN : 9781315354224
  • Genre : Mathematics
  • Total Page : 238 pages
  • Language : English
  • PDF File Size : 14,6 Mb

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