Autophagy Networks in Inflammation is popular PDF and ePub book, written by Maria Chiara Maiuri in 2016-08-17, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Autophagy Networks in Inflammation can be Read Online from any device for your convenience.
Autophagy Networks in Inflammation Book PDF Summary
Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.
Detail Book of Autophagy Networks in Inflammation PDF
- Author : Maria Chiara Maiuri
- Release : 17 August 2016
- Publisher : Springer
- ISBN : 9783319300795
- Genre : Medical
- Total Page : 403 pages
- Language : English
- PDF File Size : 13,6 Mb
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