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Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Aryl Ketones Book PDF Summary

This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.

Detail Book of Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Aryl Ketones PDF

Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of    Aryl Ketones
  • Author : Robert Doran
  • Release : 24 June 2015
  • Publisher : Springer
  • ISBN : 9783319205441
  • Genre : Science
  • Total Page : 202 pages
  • Language : English
  • PDF File Size : 17,5 Mb

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