Molecular and Clinical Advances in Anticancer Drug Resistance is popular PDF and ePub book, written by Robert F. Ozols in 2012-12-06, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Molecular and Clinical Advances in Anticancer Drug Resistance can be Read Online from any device for your convenience.
Molecular and Clinical Advances in Anticancer Drug Resistance Book PDF Summary
The importance of drug resistance in cancer chemotherapy cannot be over stated. The 500,000 patients who die every year from cancer in the United States have, in most cases, been treated with chemotherapy. Many of these patients responded initially to chemotherapy, but death resulted from the development of drug-resistant tumors. In the first volume in the series. Drug Resistance in Chemotherapy the results of comprehensive laboratory studies aimed at understanding the mechanisms for resistance to individual agents and to the development of broad cross-resistance were described. In the past 2 years there has been substantial progress in understanding the molecular biology associated with these mechanisms of drug resistance. For the first time we are starting to understand which mechanisms are playing an im portant role in human tumors, and even more importantly, clinical trials have recently been initiated in an effort to reverse specific forms of drug resistance. The purpose of this volume is to describe the new advances, both at the molecular level and in the clinic regarding mechanisms of drug resistance and potential ways this resistance can be circumvented. This volume is focused upon mechanisms of resistance associated with two major classes of anticancer drugs: alkylating agents (including cisplatin) and the natural products (e. g. , adriamycin and vinblastine). The first section of the book describes new insights into the genetic mechanisms associated with drug resistance.
Detail Book of Molecular and Clinical Advances in Anticancer Drug Resistance PDF
- Author : Robert F. Ozols
- Release : 06 December 2012
- Publisher : Springer Science & Business Media
- ISBN : 9781461538721
- Genre : Medical
- Total Page : 314 pages
- Language : English
- PDF File Size : 20,9 Mb
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