Antifolate Drugs in Cancer Therapy is popular PDF and ePub book, written by Ann L. Jackman in 1999-01-22, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Antifolate Drugs in Cancer Therapy can be Read Online from any device for your convenience.
Antifolate Drugs in Cancer Therapy Book PDF Summary
In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an important class of anticancer drugs. The distinguished contributors discuss the preclinical and clinical pharmacology of methotrexate, other dihydrofolate reductase inhibitors, 5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death. The wide and progressive scope of Antifolate Drugs in Cancer Therapy provides entré to exciting new avenues for future research, and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.
Detail Book of Antifolate Drugs in Cancer Therapy PDF
- Author : Ann L. Jackman
- Release : 22 January 1999
- Publisher : Springer Science & Business Media
- ISBN : 9781592597253
- Genre : Medical
- Total Page : 769 pages
- Language : English
- PDF File Size : 11,8 Mb
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