Advances in Rapid Sex Steroid Action is popular PDF and ePub book, written by Gabriella Castoria in 2011-12-15, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Advances in Rapid Sex Steroid Action can be Read Online from any device for your convenience.
Advances in Rapid Sex Steroid Action Book PDF Summary
Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Detail Book of Advances in Rapid Sex Steroid Action PDF
- Author : Gabriella Castoria
- Release : 15 December 2011
- Publisher : Springer Science & Business Media
- ISBN : 9781461417644
- Genre : Medical
- Total Page : 271 pages
- Language : English
- PDF File Size : 17,6 Mb
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