Advances in Down Syndrome Research is popular PDF and ePub book, written by Gert Lubec in 2013-03-13, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Advances in Down Syndrome Research can be Read Online from any device for your convenience.
Advances in Down Syndrome Research Book PDF Summary
"Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes.
Detail Book of Advances in Down Syndrome Research PDF
- Author : Gert Lubec
- Release : 13 March 2013
- Publisher : Springer Science & Business Media
- ISBN : 9783709167212
- Genre : Medical
- Total Page : 241 pages
- Language : English
- PDF File Size : 12,8 Mb
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