Pharmacokinetic Pharmacodynamic Modeling and Simulation is popular PDF and ePub book, written by Peter L. Bonate in 2006-05-14, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Pharmacokinetic Pharmacodynamic Modeling and Simulation can be Read Online from any device for your convenience.
Pharmacokinetic Pharmacodynamic Modeling and Simulation Book PDF Summary
A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. The purpose of this book is to present through theory and example how to develop pharmacokinetic models, both at an individual and population level. In order to do so, however, one must first understand linear models and then build to nonlinear models followed by linear mixed effects models and then ultimately nonlinear mixed effects models. This book develops in that manner – each chapter builds upon previous chapters by first presenting the theory and then illustrating the theory using published data sets and actual data sets that were used in the development of new chemical entities collected by the author during his years in industry. A key feature of the book is the process of modeling. Most books and manuscripts often present the final model never showing how the model evolved. In this book all examples are presented in an evolutionary manner.
Detail Book of Pharmacokinetic Pharmacodynamic Modeling and Simulation PDF
- Author : Peter L. Bonate
- Release : 14 May 2006
- Publisher : Springer Science & Business Media
- ISBN : 9780387271996
- Genre : Medical
- Total Page : 395 pages
- Language : English
- PDF File Size : 20,8 Mb
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